SLPI monoclonal antibody (M01), clone 3C6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLPI.
Immunogen
SLPI (NP_003055, 33 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SLPI expression in transfected 293T cell line by SLPI monoclonal antibody (M01), clone 3C6.
Lane 1: SLPI transfected lysate (Predicted MW: 14.52 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLPI is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SLPI
Entrez GeneID
6590GeneBank Accession#
NM_003064Protein Accession#
NP_003055Gene Name
SLPI
Gene Alias
ALK1, ALP, BLPI, HUSI, HUSI-I, MPI, WAP4, WFDC4
Gene Description
secretory leukocyte peptidase inhibitor
Omim ID
107285Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq
Other Designations
OTTHUMP00000031775|WAP four-disulfide core domain 4|antileukoproteinase|mucus proteinase inhibitor|secretory leukocyte protease inhibitor (antileukoproteinase)|seminal proteinase inhibitor
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Interactome
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