SLC6A3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SLC6A3 full-length
Host
Human
Theoretical MW (kDa)
68.5
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SLC6A3 antibody (H00006531-D01P) by Western Blots.
SDS-PAGE Gel
SLC6A3 transfected lysate.
Western Blot
Lane 1: SLC6A3 transfected lysate ( 68.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SLC6A3
Entrez GeneID
6531GeneBank Accession#
NM_001044.2Protein Accession#
NP_001035.1Gene Name
SLC6A3
Gene Alias
DAT, DAT1
Gene Description
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Gene Ontology
HyperlinkGene Summary
The dopamine transporter (DAT1) mediates the active reuptake of dopamine from the synapse and is a principal regulator of dopaminergic neurotransmission. The DAT1 gene has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse (Vandenbergh et al., 1992 [PubMed 1359373]).[supplied by OMIM
Other Designations
dopamine transporter|variable number tandem repeat (VNTR)
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Interactome
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Disease
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