SLC1A2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SLC1A2 transfected lysate.
Western Blot
Lane 1: SLC1A2 transfected lysate ( 62.10 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SLC1A2 full-length
Host
Human
Theoretical MW (kDa)
62.1
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SLC1A2 antibody (H00006506-D01P) by Western Blots.
SDS-PAGE Gel
SLC1A2 transfected lysate.
Western Blot
Lane 1: SLC1A2 transfected lysate ( 62.10 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SLC1A2
Entrez GeneID
6506GeneBank Accession#
NM_004171.2Protein Accession#
NP_004162.2Gene Name
SLC1A2
Gene Alias
EAAT2, GLT-1
Gene Description
solute carrier family 1 (glial high affinity glutamate transporter), member 2
Omim ID
600300Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glial high affinity glutamate transporter|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2|solute carrier family 1, member 2
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Interactome
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Pathway
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Disease
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