SH3BP2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SH3BP2 transfected lysate.
Western Blot
Lane 1: SH3BP2 transfected lysate ( 62.2 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SH3BP2 full-length
Host
Human
Theoretical MW (kDa)
62.2
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SH3BP2 antibody (H00006452-B01P) by Western Blots.
SDS-PAGE Gel
SH3BP2 transfected lysate.
Western Blot
Lane 1: SH3BP2 transfected lysate ( 62.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SH3BP2
Entrez GeneID
6452GeneBank Accession#
BC022996Protein Accession#
AAH22996.1Gene Name
SH3BP2
Gene Alias
3BP2, CRBM, CRPM, FLJ42079, RES4-23
Gene Description
SH3-domain binding protein 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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