SGCG monoclonal antibody (M02), clone 3C5
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of SGCG transfected lysate using anti-SGCG monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SGCG MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SGCG is 0.1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SGCG.
Immunogen
SGCG (NP_000222.1, 191 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHSHIC
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of SGCG transfected lysate using anti-SGCG monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SGCG MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SGCG is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — SGCG
Entrez GeneID
6445GeneBank Accession#
NM_000231Protein Accession#
NP_000222.1Gene Name
SGCG
Gene Alias
A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE
Gene Description
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq
Other Designations
35kD dystrophin-associated glycoprotein|OTTHUMP00000018112|gamma sarcoglycan|sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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Disease
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