SFTPC 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SFTPC full-length
Host
Human
Theoretical MW (kDa)
21.78
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SFTPC antibody (H00006440-B01) by Western Blots.
SDS-PAGE Gel
SFTPC transfected lysate.
Western Blot
Lane 1: SFTPC transfected lysate ( 21.78 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SFTPC
Entrez GeneID
6440GeneBank Accession#
NM_003018Protein Accession#
NP_003009Gene Name
SFTPC
Gene Alias
PSP-C, SFTP2, SMDP2, SP-C
Gene Description
surfactant protein C
Gene Ontology
HyperlinkGene Summary
The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. It is produced exclusively by type II alveolar epithelial cells in the lung. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark and Clark, 2005 [PubMed 15927881]). See also SFTPA1 (MIM 178630), SFTPB (MIM 178640), and SFTPD (MIM 178635).[supplied by OMIM
Other Designations
pulmonary surfactant apoprotein-2 SP-C|surfactant, pulmonary-associated protein C
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