SCN4B (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SCN4B full-length ORF (BAG37123.1, 1 a.a. - 228 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPGAGDGGKAPARWLGTGLLGLFLLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.48
Interspecies Antigen Sequence
Mouse (79); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SCN4B
Entrez GeneID
6330GeneBank Accession#
AK314531.1Protein Accession#
BAG37123.1Gene Name
SCN4B
Gene Alias
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Gene Description
sodium channel, voltage-gated, type IV, beta
Omim ID
608256Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene
Other Designations
sodium channel beta-4 subunit
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Interactome
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Disease
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