SCN3A monoclonal antibody (M06), clone 2F8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SCN3A.
Immunogen
SCN3A (NP_008853, 1861 a.a. ~ 1960 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LCESGEMDALRIQMEDRFMASNPSKVSYEPITTTLKRKQEEVSAAIIQRNFRCYLLKQRLKNISSNYNKEAIKGRIDLPIKQDMIIDKLNGNSTPEKTDG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SCN3A
Entrez GeneID
6328GeneBank Accession#
NM_006922Protein Accession#
NP_008853Gene Name
SCN3A
Gene Alias
KIAA1356, NAC3, Nav1.3
Gene Description
sodium channel, voltage-gated, type III, alpha subunit
Omim ID
182391Gene Ontology
HyperlinkGene Summary
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000041047|brain III voltage-gated sodium channel|sodium channel protein type 3 subunit alpha|sodium channel, voltage-gated, type III, alpha|sodium channel, voltage-gated, type III, alpha polypeptide
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Interactome
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Disease
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