RORA monoclonal antibody (M01), clone 4E3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RORA.
Immunogen
RORA (NP_599023, 424 a.a. ~ 523 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RORA is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — RORA
Entrez GeneID
6095GeneBank Accession#
NM_134261Protein Accession#
NP_599023Gene Name
RORA
Gene Alias
DKFZp686M2414, MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA
Gene Description
RAR-related orphan receptor A
Omim ID
600825Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
RAR-related orphan receptor alpha|ROR-alpha|retinoic acid receptor-related orphan receptor alpha|retinoid-related orphan receptor alpha|transcription factor RZR-alpha
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Interactome
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Disease
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