RLN2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RLN2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MPRLFFFHLLGVCLLLNQFSRAVADSWMEEVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETINMMSEFVANLPQELKLTLSEMQPALPQLQQHVPVLKDSSLLFEEFKKLIRNRQSEAADSSPSELKYLGLDTHSRKKRQLYSALANKCCHVGCTKRSLARFC
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — RLN2
Entrez GeneID
6019GeneBank Accession#
HQ258745.1Protein Accession#
ADR83496.1Gene Name
RLN2
Gene Alias
H2, RLXH2, bA12D24.1.1, bA12D24.1.2
Gene Description
relaxin 2
Omim ID
179740Gene Ontology
HyperlinkGene Summary
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000021027|prorelaxin H2|relaxin H2|relaxin, ovarian, of pregnancy
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Interactome
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Disease
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