RFX3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RFX3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RFX3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RFX3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RFX3
Entrez GeneID
5991GeneBank Accession#
RFX3Gene Name
RFX3
Gene Alias
MGC87155, bA32F11.1
Gene Description
regulatory factor X, 3 (influences HLA class II expression)
Omim ID
601337Gene Ontology
HyperlinkGene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals. [provided by RefSeq
Other Designations
DNA binding protein RFX3|OTTHUMP00000020993|OTTHUMP00000020994|OTTHUMP00000044314|regulatory factor X3
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Interactome
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