RBBP4 monoclonal antibody (M02), clone 4A5
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More Files
- More Functions
Western Blot (Cell lysate)
RBBP4 monoclonal antibody (M02), clone 4A5 Western Blot analysis of RBBP4 expression in Hela S3 NE ( Cat # L013V3 ).
Immunofluorescence
Immunofluorescence of monoclonal antibody to RBBP4 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (38.21 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RBBP4.
Immunogen
RBBP4 (NP_005601, 316 a.a. ~ 426 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS*
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RBBP4 monoclonal antibody (M02), clone 4A5 Western Blot analysis of RBBP4 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to RBBP4 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RBBP4
Entrez GeneID
5928GeneBank Accession#
NM_005610Protein Accession#
NP_005601Gene Name
RBBP4
Gene Alias
NURF55, RBAP48
Gene Description
retinoblastoma binding protein 4
Omim ID
602923Gene Ontology
HyperlinkGene Summary
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
MSI1 protein homolog|OTTHUMP00000009691|chromatin assembly factor/CAF-1 p48 subunit|retinoblastoma-binding protein 4|retinoblastoma-binding protein p48
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Interactome
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Disease
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