PVRL2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PVRL2 transfected lysate.
Western Blot
Lane 1: PVRL2 transfected lysate ( 51.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PVRL2 full-length
Host
Human
Theoretical MW (kDa)
51.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PVRL2 antibody (H00005819-B01) by Western Blots.
SDS-PAGE Gel
PVRL2 transfected lysate.
Western Blot
Lane 1: PVRL2 transfected lysate ( 51.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PVRL2
Entrez GeneID
5819GeneBank Accession#
NM_002856.2Protein Accession#
-Gene Name
PVRL2
Gene Alias
CD112, HVEB, PRR2, PVRR2
Gene Description
poliovirus receptor-related 2 (herpesvirus entry mediator B)
Omim ID
600798Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
herpesvirus entry mediator B|herpesvirus entry protein B|nectin 2|poliovirus receptor related 2|poliovirus receptor-like 2
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Interactome
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Pathway
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Disease
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