PTPRN2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of PTPRN2 transfected lysate using rabbit polyclonal anti-PTPRN2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PTPRN2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of PTPRN2 transfected lysate using rabbit polyclonal anti-PTPRN2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PTPRN2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-PTPRN2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-PTPRN2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — PTPRN2
Entrez GeneID
5799Gene Name
PTPRN2
Gene Alias
IA-2beta, IAR, ICAAR, PTPRP
Gene Description
protein tyrosine phosphatase, receptor type, N polypeptide 2
Omim ID
601698Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
IAR/receptor-like protein-tyrosine phosphatase|phogrin|protein tyrosine phosphatase receptor pi|tyrosine phosphatase IA-2 beta
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Interactome
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Pathway
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Disease
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