PTPN9 monoclonal antibody (M04), clone 2F12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PTPN9.
Immunogen
PTPN9 (NP_002824.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTPN9 expression in transfected 293T cell line by PTPN9 monoclonal antibody (M04), clone 2F12.
Lane 1: PTPN9 transfected lysate (Predicted MW: 65.23 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTPN9 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — PTPN9
Entrez GeneID
5780GeneBank Accession#
NM_002833Protein Accession#
NP_002824.1Gene Name
PTPN9
Gene Alias
MEG2, PTPMEG2
Gene Description
protein tyrosine phosphatase, non-receptor type 9
Omim ID
600768Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq
Other Designations
PTPase-MEG2|protein-tyrosine phosphatase MEG2
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