PTHLH 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
Western Blot
Lane 1: PTHLH transfected lysate ( 20.2 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
PTHLH transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTHLH full-length
Host
Human
Theoretical MW (kDa)
19.58
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTHLH antibody (H00005744-B01) by Western Blots.
Western Blot
Lane 1: PTHLH transfected lysate ( 20.2 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
PTHLH transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTHLH
Entrez GeneID
5744GeneBank Accession#
NM_198965Protein Accession#
NP_945316Gene Name
PTHLH
Gene Alias
HHM, MGC14611, PLP, PTHR, PTHRP
Gene Description
parathyroid hormone-like hormone
Omim ID
168470Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq
Other Designations
PTH-related protein|humoral hypercalcemia of malignancy|osteostatin|parathyroid hormone-like protein|parathyroid hormone-like related protein|parathyroid hormone-related protein|parathyroid-like protein
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Interactome
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Disease
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