PTHLH monoclonal antibody (M01), clone 3H1-5G8
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to PTHLH on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTHLH is approximately 0.3ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to PTHLH on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (44.99 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PTHLH.
Immunogen
PTHLH (AAH05961, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MQRRLVQQWSVAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR
Host
Mouse
Reactivity
Human
Isotype
IgG2b kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (44.99 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to PTHLH on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTHLH is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to PTHLH on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — PTHLH
Entrez GeneID
5744GeneBank Accession#
BC005961Protein Accession#
AAH05961Gene Name
PTHLH
Gene Alias
HHM, MGC14611, PLP, PTHR, PTHRP
Gene Description
parathyroid hormone-like hormone
Omim ID
168470Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq
Other Designations
PTH-related protein|humoral hypercalcemia of malignancy|osteostatin|parathyroid hormone-like protein|parathyroid hormone-like related protein|parathyroid hormone-related protein|parathyroid-like protein
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Interactome
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Disease
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Publication Reference
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The Expression of PTHLH in Human Gastric Mucosa Enterochromaffin-Like Cells.
Liu C, Chen J, Guo Y, Yang L, Zhao C, Bai L.
Digestive Diseases and Sciences 2011 Apr; 56(4):993.
Application：IHC-P, Human, Enterochromaffin-like cells, Gastric fundic mucosa.
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The Expression of PTHLH in Human Gastric Mucosa Enterochromaffin-Like Cells.
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