KLK7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KLK7 full-length
Host
Human
Theoretical MW (kDa)
27.94
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-KLK7 antibody (H00005650-B01) by Western Blots.
SDS-PAGE Gel
KLK7 transfected lysate
Western Blot
Lane 1: KLK7 transfected lysate ( 27.94 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KLK7
Entrez GeneID
5650GeneBank Accession#
BC032005Protein Accession#
AAH32005Gene Name
KLK7
Gene Alias
PRSS6, SCCE
Gene Description
kallikrein-related peptidase 7
Omim ID
604438Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq
Other Designations
kallikrein 7 (chymotryptic, stratum corneum)|protease, serine, 6|signal protein|stratum corneum chymotryptic enzyme
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Interactome
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Disease
- Asthma
- Birth Weight
- Dermatitis
- Eczema
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Leukemia
- Meningeal Neoplasms
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