PRODH monoclonal antibody (M01), clone 3A9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PRODH.
Immunogen
PRODH (NP_057419, 441 a.a. ~ 540 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to PRODH on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRODH is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PRODH
Entrez GeneID
5625GeneBank Accession#
NM_016335Protein Accession#
NP_057419Gene Name
PRODH
Gene Alias
FLJ33744, HSPOX2, MGC148078, MGC148079, PIG6, POX, PRODH1, PRODH2, SCZD4, TP53I6
Gene Description
proline dehydrogenase (oxidase) 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000196495|proline dehydrogenase 1|proline oxidase 2|proline oxidase, mitochondrial|tumor protein p53 inducible protein 6
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Interactome
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Pathway
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Disease
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