PMS2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PMS2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PMS2 expression in human placenta.
Western Blot (Transfected lysate)
Western Blot analysis of PMS2 expression in transfected 293T cell line (H00005395-T02) by PMS2 MaxPab polyclonal antibody.
Lane 1: PMS2 transfected lysate(95.80 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PMS2 protein.
Immunogen
PMS2 (NP_000526.1, 1 a.a. ~ 862 a.a) full-length human protein.
Sequence
MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PMS2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PMS2 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of PMS2 expression in transfected 293T cell line (H00005395-T02) by PMS2 MaxPab polyclonal antibody.
Lane 1: PMS2 transfected lysate(95.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PMS2
Entrez GeneID
5395GeneBank Accession#
NM_000535Protein Accession#
NP_000526.1Gene Name
PMS2
Gene Alias
HNPCC4, PMS2CL, PMSL2
Gene Description
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq
Other Designations
DNA mismatch repair protein|H_DJ0042M02.9|PMS2 postmeiotic segregation increased 2|mismatch repair endonuclease|postmeiotic segregation increased 2
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Interactome
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Pathway
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Disease
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