PLG monoclonal antibody (M01), clone 2A10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PLG.
Immunogen
PLG (AAH60513, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PLG is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PLG
Entrez GeneID
5340GeneBank Accession#
BC060513Protein Accession#
AAH60513Gene Name
PLG
Gene Alias
DKFZp779M0222
Gene Description
plasminogen
Gene Ontology
HyperlinkGene Summary
Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU; MIM 191840) and tissue plasminogen activator (PLAT; MIM 173370). The main function of plasmin is to dissolve fibrin (see, e.g., FGA, MIM 134820) clots. Plasmin, like trypsin, belongs to the family of serine proteinases (Miyata et al., 1982 [PubMed 6216475]; Forsgren et al., 1987 [PubMed 3030813]).[supplied by OMIM
Other Designations
OTTHUMP00000017544
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Interactome
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Pathway
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Disease
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Publication Reference
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Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression.
Jeon J, Jeong JH, Baek JH, Koo HJ, Park WH, Yang JS, Yu MH, Kim S, Pak YK.
PLoS Computational Biology 2011 Jun; 7(6):e1002093.
Application:WB-Ce, Human, 143B TK- osteosarcoma cells.
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Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression.
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