PKD2 monoclonal antibody (M02), clone 1G3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PKD2.
Immunogen
PKD2 (NP_000288, 261 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PKD2 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PKD2
Entrez GeneID
5311GeneBank Accession#
NM_000297Protein Accession#
NP_000288Gene Name
PKD2
Gene Alias
APKD2, MGC138466, MGC138468, PC2, PKD4
Gene Description
polycystic kidney disease 2 (autosomal dominant)
Omim ID
173910Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq
Other Designations
polycystin 2|polycystwin
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Interactome
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Disease
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