PI3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PI3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PI3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PI3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PI3
Entrez GeneID
5266GeneBank Accession#
PI3Gene Name
PI3
Gene Alias
ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
Gene Description
peptidase inhibitor 3, skin-derived
Omim ID
182257Gene Ontology
HyperlinkGene Summary
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq
Other Designations
OTTHUMP00000031100|WAP four-disulfide core domain 14|elafin|elastase-specific inhibitor|protease inhibitor 3, skin-derived (SKALP)|skin-derived antileukoproteinase
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Interactome
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Disease
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