ATP8B1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ATP8B1 partial ORF ( NP_005594.1, 471 a.a. - 551 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
INGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.65
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ATP8B1
Entrez GeneID
5205GeneBank Accession#
NM_005603Protein Accession#
NP_005594.1Gene Name
ATP8B1
Gene Alias
ATPIC, BRIC, FIC1, PFIC, PFIC1
Gene Description
ATPase, class I, type 8B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. [provided by RefSeq
Other Designations
E1-E2 ATPase|OTTHUMP00000163615|phospholipid-transporting ATPase IC
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Interactome
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