PCSK2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PCSK2 transfected lysate.
Western Blot
Lane 1: PCSK2 transfected lysate ( 70.60 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PCSK2 full-length
Host
Human
Theoretical MW (kDa)
70.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PCSK2 antibody (H00005126-D01P) by Western Blots.
SDS-PAGE Gel
PCSK2 transfected lysate.
Western Blot
Lane 1: PCSK2 transfected lysate ( 70.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PCSK2
Entrez GeneID
5126GeneBank Accession#
NM_002594.2Protein Accession#
NP_002585.2Gene Name
PCSK2
Gene Alias
NEC2, PC2, SPC2
Gene Description
proprotein convertase subtilisin/kexin type 2
Omim ID
162151Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
Other Designations
KEX2-like endoprotease 2|OTTHUMP00000030330|neuroendocrine convertase 2|prohormone convertase 2|subtilisin-like prohormone convertases
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Disease
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