PCSK5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PCSK5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PCSK5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PCSK5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PCSK5
Entrez GeneID
5125GeneBank Accession#
PCSK5Gene Name
PCSK5
Gene Alias
PC5, PC6, PC6A, SPC6
Gene Description
proprotein convertase subtilisin/kexin type 5
Omim ID
600488Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. [provided by RefSeq
Other Designations
OTTHUMP00000021497|OTTHUMP00000063532|prohormone convertase 5|proprotein convertase PC5|protease PC6|subtilisin/kexin-like protease PC5
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Interactome
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Disease
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