PAPPA monoclonal antibody (M01), clone 1G3
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More Files
- More Functions
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PAPPA.
Immunogen
PAPPA (NP_002572, 85 a.a. ~ 194 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (88)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PAPPA
Entrez GeneID
5069GeneBank Accession#
NM_002581Protein Accession#
NP_002572Gene Name
PAPPA
Gene Alias
ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1
Gene Description
pregnancy-associated plasma protein A, pappalysin 1
Omim ID
176385Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq
Other Designations
OTTHUMP00000022806|aspecific BCL2 ARE-binding protein 2|differentially placenta 1 expressed protein|insulin-like growth factor-dependent IGF binding protein-4 protease|pregnacy-associated plasma protein A|pregnancy-associated plasma protein A
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Interactome
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Disease
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