NFYB DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NFYB DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQQIQFS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — NFYB
Entrez GeneID
4801GeneBank Accession#
NM_006166.3Protein Accession#
NP_006157.1Gene Name
NFYB
Gene Alias
CBF-A, CBF-B, HAP3, NF-YB
Gene Description
nuclear transcription factor Y, beta
Omim ID
189904Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq
Other Designations
CCAAT-binding transcription factor subunit A|Transcription factor NF-Y, B subunit
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Interactome
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Pathway
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