NEU1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (35.13 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant NEU1.
Immunogen
NEU1 (NP_000425, 334 a.a. ~ 415 a.a) partial recombinant protein with GST tag.
Sequence
NPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (82)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.13 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NEU1
Entrez GeneID
4758GeneBank Accession#
NM_000434Protein Accession#
NP_000425Gene Name
NEU1
Gene Alias
FLJ93471, NANH, NEU, SIAL1
Gene Description
sialidase 1 (lysosomal sialidase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq
Other Designations
G9 sialidase|N-acetyl-alpha-neuraminidase 1|OTTHUMP00000029419|acetylneuraminyl hydrolase|exo-alpha-sialidase|lysosomal sialidase|neuraminidase
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Interactome
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Pathway
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Disease
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