NCBP1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human NCBP1 partial ORF ( NP_002477, 2 a.a. - 99 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NCBP1
Entrez GeneID
4686GeneBank Accession#
NM_002486Protein Accession#
NP_002477Gene Name
NCBP1
Gene Alias
CBP80, MGC2087, NCBP
Gene Description
nuclear cap binding protein subunit 1, 80kDa
Omim ID
600469Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq
Other Designations
OTTHUMP00000021753
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