MSH2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MSH2 full-length
Host
Human
Theoretical MW (kDa)
104.7
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MSH2 antibody (H00004436-B01) by Western Blots.
SDS-PAGE Gel
MSH2 transfected lysate.
Western Blot
Lane 1: MSH2 transfected lysate ( 104.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MSH2
Entrez GeneID
4436GeneBank Accession#
NM_000251Protein Accession#
NP_000242Gene Name
MSH2
Gene Alias
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Gene Description
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Gene Ontology
HyperlinkGene Summary
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq
Other Designations
mutS homolog 2
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Interactome
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Pathway
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Disease
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