MICB DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MICB DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAEDVLGAETWDTETEDLTENGQDLRRTLTHIKDQKGVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MICB
Entrez GeneID
4277GeneBank Accession#
BC044218Protein Accession#
AAH44218.1Gene Name
MICB
Gene Alias
PERB11.2
Gene Description
MHC class I polypeptide-related sequence B
Omim ID
602436Gene Ontology
HyperlinkGene Summary
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq
Other Designations
MHC class I chain-related protein B|MHC class I mic-B antigen|MHC class I molecule|MHC class I-like molecule PERB11.2-IMX|OTTHUMP00000029089|OTTHUMP00000035091|OTTHUMP00000035588|stress inducible class I homolog
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Interactome
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Pathway
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Disease
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