MFNG DNAxPab
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More Files
- More Functions
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MFNG DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MFNG
Entrez GeneID
4242GeneBank Accession#
NM_002405.2Protein Accession#
NP_002396.2Gene Name
MFNG
Gene Alias
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Gene Description
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Omim ID
602577Gene Ontology
HyperlinkGene Summary
This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
Other Designations
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|OTTHUMP00000043697|OTTHUMP00000043698|OTTHUMP00000043700|beta-1,3-N-acetylglucosaminyltransferase manic fringe|manic fringe homolog
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Interactome
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Pathway
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Disease
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