MEN1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MEN1 full-length
Host
Human
Theoretical MW (kDa)
63.36
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MEN1 antibody (H00004221-B01) by Western Blots.
SDS-PAGE Gel
MEN1 transfected lysate.
Western Blot
Lane 1: MEN1 transfected lysate ( 63.36 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MEN1
Entrez GeneID
4221GeneBank Accession#
BC002544.2Protein Accession#
-Gene Name
MEN1
Gene Alias
MEAI, SCG2
Gene Description
multiple endocrine neoplasia I
Gene Ontology
HyperlinkGene Summary
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000042868|OTTHUMP00000070176|OTTHUMP00000070180|OTTHUMP00000070184|endocrine adenomatosis, multiple|menin
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Interactome
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Disease
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