MAN2A1 monoclonal antibody (M01), clone 1G9
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More Files
- More Functions
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAN2A1.
Immunogen
MAN2A1 (NP_002363, 1045 a.a. ~ 1144 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (74)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MAN2A1
Entrez GeneID
4124GeneBank Accession#
NM_002372Protein Accession#
NP_002363Gene Name
MAN2A1
Gene Alias
GOLIM7, MANA2, MANII
Gene Description
mannosidase, alpha, class 2A, member 1
Omim ID
154582Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq
Other Designations
Golgi alpha-mannosidase II|golgi integral membrane protein 7|mannosidase, alpha type II|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
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Interactome
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Pathway
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Disease
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Publication Reference
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Quantitative Proteomic Analysis of PCSK9 Gain of Function in Human Hepatic HuH7 Cells.
Denis N, Palmer-Smith H, Elisma F, Busuttil A, Wright TG, Khalil MB, Prat A, Seidah NG, Chretien M, Mayne J, Figeys D.
J Proteome Res 2011 Mar; 10:2011.
Application：WB, Mouse, Liver.
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Quantitative Proteomic Analysis of PCSK9 Gain of Function in Human Hepatic HuH7 Cells.
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