LSS monoclonal antibody (M01), clone 2E4
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to LSS on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
Immunofluorescence
Immunofluorescence of monoclonal antibody to LSS on HeLa cell . [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LSS.
Immunogen
LSS (NP_001001438.1, 633 a.a. ~ 732 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86)
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to LSS on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to LSS on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — LSS
Entrez GeneID
4047GeneBank Accession#
NM_001001438Protein Accession#
NP_001001438.1Gene Name
LSS
Gene Alias
FLJ25486, FLJ35015, FLJ39450, FLJ46393, OSC
Gene Description
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Omim ID
600909Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms
Other Designations
2,3-epoxysqualene--lanosterol cyclase|lanosterol synthase
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Interactome
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Pathway
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Disease
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