LMX1A DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human LMX1A DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — LMX1A
Entrez GeneID
4009GeneBank Accession#
NM_001033507.1Protein Accession#
NP_001028679.1Gene Name
LMX1A
Gene Alias
LMX-1, LMX1, LMX1.1, MGC87616
Gene Description
LIM homeobox transcription factor 1, alpha
Omim ID
600298Gene Ontology
HyperlinkGene Summary
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Other Designations
OTTHUMP00000032530|OTTHUMP00000032531|OTTHUMP00000032532
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Disease
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