LGALS3BP rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LGALS3BP peptide using ARM Technology.
Immunogen
A synthetic peptide of human LGALS3BP is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LGALS3BP peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LGALS3BP
Entrez GeneID
3959GeneBank Accession#
LGALS3BPGene Name
LGALS3BP
Gene Alias
90K, BTBD17B, MAC-2-BP
Gene Description
lectin, galactoside-binding, soluble, 3 binding protein
Omim ID
600626Gene Ontology
HyperlinkGene Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq
Other Designations
L3 antigen|Mac-2-binding protein|galectin 3 binding protein|serum protein 90K
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Interactome
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Toll Free : +1-877-853-6098 - +1-909-992-3401
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