KLRC2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KLRC2 full-length
Host
Human
Theoretical MW (kDa)
26.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FASTKantibody (H00003822-B01)byWesternBlots.
SDS-PAGE Gel
KLRC2 transfected lysate.
Western Blot
Lane 1: KLRC2 transfected lysate ( 26.1 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KLRC2
Entrez GeneID
3822GeneBank Accession#
BC093644.1Protein Accession#
AAH93644.1Gene Name
KLRC2
Gene Alias
CD159c, MGC138244, NKG2-C, NKG2C
Gene Description
killer cell lectin-like receptor subfamily C, member 2
Omim ID
602891Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq
Other Designations
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