KCNJ1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human KCNJ1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — KCNJ1
Entrez GeneID
3758GeneBank Accession#
NM_153765.1Protein Accession#
NP_722449.1Gene Name
KCNJ1
Gene Alias
KIR1.1, ROMK, ROMK1
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 1
Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ATP-regulated potassium channel ROM-K|ATP-sensitive inward rectifier potassium channel 1|OTTHUMP00000045938|inwardly rectifying K+ channel|potassium inwardly-rectifying channel J1
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Interactome
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Disease
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