IL1A 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IL1A full-length
Host
Human
Theoretical MW (kDa)
30.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IL1A antibody (H00003552-D01P) by Western Blots.
SDS-PAGE Gel
IL1A transfected lysate.
Western Blot
Lane 1: IL1A transfected lysate ( 30.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IL1A
Entrez GeneID
3552GeneBank Accession#
NM_000575Protein Accession#
NP_000566.3Gene Name
IL1A
Gene Alias
IL-1A, IL1, IL1-ALPHA, IL1F1
Gene Description
interleukin 1, alpha
Omim ID
147760Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq
Other Designations
IL1A (IL1F1)|hematopoietin-1|preinterleukin 1 alpha|pro-interleukin-1-alpha
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Interactome
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Pathway
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Disease
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