HYAL1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
HYAL1 transfected lysate.
Western Blot
Lane 1: HYAL1 transfected lysate ( 28 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HYAL1 full-length
Host
Human
Theoretical MW (kDa)
28
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HYAL1 antibody (H00003373-B01) by Western Blots.
SDS-PAGE Gel
HYAL1 transfected lysate.
Western Blot
Lane 1: HYAL1 transfected lysate ( 28 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HYAL1
Entrez GeneID
3373GeneBank Accession#
NM_153283.1Protein Accession#
-Gene Name
HYAL1
Gene Alias
HYAL-1, LUCA1, MGC45987, NAT6
Gene Description
hyaluronoglucosaminidase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hyaluronidase 1|plasma hyaluronidase|tumor suppressor LUCA-1
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Interactome
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Pathway
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Disease
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