HTR5A monoclonal antibody (M01), clone 10D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HTR5A.
Immunogen
HTR5A (NP_076917, 223 a.a. ~ 282 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (88)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.34 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HTR5A is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — HTR5A
Entrez GeneID
3361GeneBank Accession#
NM_024012Protein Accession#
NP_076917Gene Name
HTR5A
Gene Alias
5-HT5A, MGC138226
Gene Description
5-hydroxytryptamine (serotonin) receptor 5A
Omim ID
601305Gene Ontology
HyperlinkGene Summary
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq
Other Designations
5-hydroxytryptamine receptor 5A
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Interactome
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Pathway
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