HABP2 monoclonal antibody (M01), clone 1H4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HABP2.
Immunogen
HABP2 (NP_004123, 105 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRG
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of HABP2 transfected lysate using anti-HABP2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HABP2 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HABP2 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — HABP2
Entrez GeneID
3026GeneBank Accession#
NM_004132Protein Accession#
NP_004123Gene Name
HABP2
Gene Alias
FSAP, HABP, HGFAL, PHBP
Gene Description
hyaluronan binding protein 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. [provided by RefSeq
Other Designations
OTTHUMP00000020505|factor VII activating protein|hepatocyte growth factor activator-like protein|hyaluronic acid binding protein 2|plasma hyaluronan binding protein
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Interactome
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Disease
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Publication Reference
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Anti-Adipogenic Polyphenols of Water Shield Suppress TNF-α-Induced Cell Damage and Enhance Expression of HAS2 and HAPB2 in Adiponectin-Treated Dermal Fibroblasts.
Hiroshi Shimoda, Seikou Nakamura, Shoketsu Hitoe, Shuko Terazawa, Junji Tanaka, Takahiro Matsumoto, Hisashi Matsuda.
Natural Products Chemistry & Research 2014 Aug; 2(5):1000146.
Application:WB-Ce, Human, TIG-108 cells.
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Anti-Adipogenic Polyphenols of Water Shield Suppress TNF-α-Induced Cell Damage and Enhance Expression of HAS2 and HAPB2 in Adiponectin-Treated Dermal Fibroblasts.
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