GTF2I (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human GTF2I full-length ORF (AAH04472, 1 a.a. - 274 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGVSFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.88
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GTF2I
Entrez GeneID
2969GeneBank Accession#
BC004472Protein Accession#
AAH04472Gene Name
GTF2I
Gene Alias
BAP-135, BAP135, BTKAP1, DIWS, FLJ38776, FLJ56355, IB291, SPIN, TFII-I, WBS, WBSCR6
Gene Description
general transcription factor II, i
Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21. [provided by RefSeq
Other Designations
BTK-associated protein, 135kD|Bruton tyrosine kinase-associated protein 135|Williams-Beuren syndrome chromosome region 6
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Interactome
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Pathway
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