GRIA4 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GRIA4 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GRIA4
Entrez GeneID
2893GeneBank Accession#
NM_001077244.1Protein Accession#
NP_001070712.1Gene Name
GRIA4
Gene Alias
GLUR4, GLUR4C, GLURD
Gene Description
glutamate receptor, ionotrophic, AMPA 4
Omim ID
138246Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq
Other Designations
AMPA-selective glutamate receptor 4|glutamate receptor 4
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Interactome
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