GRIA3 monoclonal antibody (M04), clone 3D10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GRIA3.
Immunogen
GRIA3 (NP_000819, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GRIA3 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — GRIA3
Entrez GeneID
2892GeneBank Accession#
NM_000828Protein Accession#
NP_000819Gene Name
GRIA3
Gene Alias
GLUR-C, GLUR-K3, GLUR3, GLURC, MRX94
Gene Description
glutamate receptor, ionotrophic, AMPA 3
Omim ID
305915Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq
Other Designations
OTTHUMP00000024261|OTTHUMP00000024262|dJ1171F9.1|glutamate receptor 3|glutamate receptor C|glutamate receptor subunit 3
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Interactome
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