GCLM MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GCLM protein.
Immunogen
GCLM (NP_002052.1, 1 a.a. ~ 274 a.a) full-length human protein.
Sequence
MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GCLM expression in transfected 293T cell line (H00002730-T01) by GCLM MaxPab polyclonal antibody.
Lane 1: GCLM transfected lysate(30.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of GCLM transfected lysate using anti-GCLM MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with GCLM purified MaxPab mouse polyclonal antibody (B01P) (H00002730-B01P). -
Gene Info — GCLM
Entrez GeneID
2730GeneBank Accession#
NM_002061.2Protein Accession#
NP_002052.1Gene Name
GCLM
Gene Alias
GLCLR
Gene Description
glutamate-cysteine ligase, modifier subunit
Omim ID
601176Gene Ontology
HyperlinkGene Summary
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq
Other Designations
GSC light chain|OTTHUMP00000012299|gamma-glutamylcysteine synthetase|glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)|glutamate-cysteine ligase regulatory protein
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Interactome
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Pathway
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Disease
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