GCNT2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GCNT2 full-length
Host
Human
Theoretical MW (kDa)
44.33
Interspecies Antigen Sequence
Mouse (77); Rat (74)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GCNT2 antibody (H00002651-B01) by Western Blots.
SDS-PAGE Gel
GCNT2 transfected lysate.
Western Blot
Lane 1: GCNT2 transfected lysate ( 44.33 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GCNT2
Entrez GeneID
2651GeneBank Accession#
NM_145655.3Protein Accession#
NP_663630.2Gene Name
GCNT2
Gene Alias
CCAT, GCNT2C, GCNT5, IGNT, II, MGC163396, NACGT1, NAGCT1, ULG3, bA360O19.2, bA421M1.1
Gene Description
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
I beta-1,6-N-acetylglucosaminyltransferase|I-branching beta-1,6-acetylglucosaminyltransferase|Ii blood group|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase|OTTHUMP00000016015|OTTHUMP00000016018|OTTHUMP00000016021|beta-1,6-N-acetylglucosami
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Interactome
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Pathway
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Disease
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