GATM monoclonal antibody (M08A), clone 2H7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GATM.
Immunogen
GATM (NP_001473.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTY
Host
Mouse
Reactivity
Human
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GATM
Entrez GeneID
2628GeneBank Accession#
NM_001482Protein Accession#
NP_001473.1Gene Name
GATM
Gene Alias
AGAT, AT
Gene Description
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Omim ID
602360Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq
Other Designations
L-arginine:glycine amidinotransferase|transamidinase
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Interactome
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Pathway
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Disease
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